Garysburg is a town in Northampton County, North Carolina, United States. The population was 1,254 at the 2000 census. It is part of the Roanoke Rapids, North Carolina Micropolitan Statistical Area.
Garysburg is located at 36°26′59″N 77°33′35″W / 36.44972°N 77.55972°W / 36.44972; -77.55972 (36.449853, -77.559830).
According to the United States Census Bureau, the town has a total area of 1.0 square miles (2.5 km²), all of it land.