Named for Venice (the Most Serene Republic), La Serenissima is located near the Pacific Caost Trail in San Diego North County. Its 25 acres are home to six varietals. All its grapes are grown free of fertilizers, and the wines are handcrafted using traditional Italian methods, aged in oak casks and bottled on site. La Serenissima's wines may be purchased at a number of stores in the San Diego area or directly from the website and shipped anywhere in the U.S.