The Vaisar Laboratory, located within the Diabetes Center of Excellence in Seattle, WA, is dedicated to investigating the molecular mechanisms by which lipoproteins contribute to the development and progression of heart disease, stroke, and Alzheimer's disease. Led by Principal Investigator Dr. Tomas Vaisar, the lab utilizes state-of-the-art quantitative mass spectrometry techniques to study the role of metabolic diseases in cardiovascular disease.
Current research projects at the Vaisar Laboratory focus on HDL as a carrier of biomarkers for cardiovascular disease, the role of triglyceride-rich lipoproteins in residual cardiovascular risk, and the impact of proteolysis on the pathogenesis of cardiovascular events. The lab also specializes in applying quantitative proteomics to clinical and translational studies, aiming to discover and validate biomarkers for cardiovascular disease and cognitive impairment.
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