Threshold Pharmaceuticals is a biotechnology firm with late-stage clinical programs that are focused on the discovery, development and commercialization of small-molecule therapeutics. The therapeutics are based on metabolic targeting, an approach that may help to treat solid tumors and certain other diseases. By selectively targeting tumor cells and abnormally proliferating cells, the company is building a pipeline of drug candidates that may possibly be more effective and less toxic to healthy tissues than conventional drugs. Threshold Pharmaceuticals' initial clinical focus is the treatment of cancer and benign prostatic hyperplasia, a disease afflicting millions of men worldwide. The company is located in Redwood City, Calif.
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