Irene Map
Irene is a city in Clay, Turner, and Yankton counties in the U.S. state of South Dakota. The population was 420 at the 2010 census.
Irene is located at 43°5?1?N 97°9?24?W / 43.08361°N 97.15667°W / 43.08361; -97.15667 (43.083655, -97.156594).
According to the United States Census Bureau, the city has a total area of 0.2 square mile (0.6 km²), all land.
Nearby cities include Centerville, Mission Hill, Gayville, Hurley, Davis.