Mayo Map
Mayo is a census-designated place (CDP) in Spartanburg County, South Carolina, United States. The population was 1,592 at the 2010 census.
Mayo is located at 35°5?17?N 81°51?4?W / 35.08806°N 81.85111°W / 35.08806; -81.85111 (35.088031, -81.851034).
According to the United States Census Bureau, the CDP has a total area of 3.1 square miles (8.1 km²), all of it land.
Nearby cities include Spartanburg, Gaffney, Henrietta, Inman, Pacolet.