DeSoto County Map
The County of DeSoto is located in the State of Mississippi. Find directions to DeSoto County, browse local businesses, landmarks, get current traffic estimates, road conditions, and more. According to the 2020 US Census the DeSoto County population is estimated at 188,275 people. The DeSoto County time zone is Central Daylight Time which is 6 hours behind Coordinated Universal Time (UTC).
Nearby counties include Crittenden County, Marshall County, Tate County, Tunica County, Shelby County.
Top cities include Southaven, Olive Branch, Horn Lake, Hernando, Walls