Amondys 45 is a medication used to treat patients with Duchenne muscular dystrophy (DMD) who have a specific mutation in the dystrophin gene that can be treated by skipping exon 45. It works by increasing dystrophin production in skeletal muscle. Amondys 45 is administered through intravenous infusion once a week and is available in a single-dose vial. Common side effects include upper respiratory tract infection, cough, fever, headache, joint pain, and pain in the mouth and throat. Patients receiving Amondys 45 should be monitored for potential allergic reactions and kidney damage.
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