Paramag Biosciences is a cutting-edge biotechnology company based in Davis, CA, specializing in the development of innovative solutions for combating degenerative diseases caused by protein misfolding. Their groundbreaking technology, based on years of research by Dr. John Voss at the University of California, Davis, utilizes spin label chemistry to engineer proprietary spin labeled antioxidants that selectively bind to amyloid and provide neuronal protection from the toxic effects of amyloid-beta. These neuroprotective molecules, known as paramagnetic amyloid ligands (PALs), not only offer therapeutic potential but can also be visualized in the brain using Magnetic Resonance Imaging.
With a focus on both therapy and diagnostics, Paramag Biosciences aims to design and develop novel, paramagnetic catalytic antioxidants that can enter cells and prevent the harmful consequences of protein misfolding. Their theranostic paradigm using PALs combines diagnostic and therapeutic applications, allowing for a single agent to diagnose, monitor, and treat degenerative diseases. Led by Dr. John Voss, a renowned expert in biophysical methods and the structural basis for Alzheimer's Disease, and supported by a team of experienced scientists and advisors, Paramag Biosciences is at the forefront of personalized and precise approaches to combat protein misfolding diseases.
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